I think Barcelona will win the league, but I also believe it is time for some upset, and maybe Valencia or Sevilla could win it. So my prediction is that either of those 3 teams will win it (although, I would like to see how Sevilla handles things without Alves, the rest of their team is pretty good, but to lose the star of the team is always a big blow).
Madrid would have won it if they would have left Capello there. Not only are they building a new team once again, Shuster is under the obligation to play nice football + win the league, and he won't be able to handle it. Unless all their friendlies have been a scheme, I highly doubt he will be able to do anything, and his head alongside Calderon's will roll. I actually feel pity for him, cause this is the type of task that a relative new coach shouldn't get just yet, Madrid had to look for someone with more credentials. On top of that, their only good DM (as Shuster just doesn't like anything that Capello brought...*cough*Gago*cough*), Diarra, will be missing for a month do to the African Cup (spect to see lots of goals against them or Gago stepping up to the ocassion).
Celta is relegated...it's going to be a really weird miracle to see them winning La Liga
.
Edit: I changed Celta for Real Zaragoza, they have a nice team too, but at most I see them reaching the 4th place.